1/10/2017

Statistical analysis of quantitative genetics

What we will cover

  • genomic relationships
  • genomic selection
  • genome-enabled prediction
  • additive and non-additive effects
  • genome-wide association study
  • genomic heritability
  • statistical genomics of disease
  • population stratification
  • multiple-trait model
  • causal inference

Assignments

  • hands-on analysis of simulated and real genomic data
  • no mideterm exam
  • final exam
  • 15 minutes presentation
  • Rstudio + R Markdown + knitr
  • Jupyter Notebook

Reproducible Research

Course website

Prediction vs. Inference - 1

  • Inference
    • effect of allele substitution
    • variance component estimation
  • Prediction
    • prediction of yet-to-be observed phenotypes
    • genomic selection

Prediction vs. Inference - 2

Bibliography